Why does impaired neural signal transmission often persist following a concussion, even after macroscopic brain imaging appears normal?

💡 Explanation

Persistent signal transmission impairment after concussion arises because axonal injury triggers diffuse shear strain, causing axonal swelling and disconnection, disrupting normal nerve impulse propagation. Therefore, disrupted axonal transport persists rather than complete recovery of cerebral blood flow or glial function immediately resolving the signal deficits.

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