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Human Body & Health

Why does skin graft contraction occur during wound healing?

A)Keratinocyte proliferation exceeds collagen deposition
B)Reduced blood flow inhibits myofibroblast activity
C)Myofibroblasts exert tension on collagen fibers
D)Excessive elastin production reduces skin flexibility

💡 Explanation

Skin graft contraction happens because myofibroblasts differentiate and exert tension on the newly deposited collagen fibers in the wound bed, leading to shrinkage of the graft. Therefore, the correct answer is myofibroblast contraction; rather than proliferation or elastin production, which don't explain the tensile forces.

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