Why does sustained hypertension typically lead to increased fluid filtration into tissues and peripheral edema?

💡 Explanation

Hypertension increases hydrostatic pressure within capillaries, driving more fluid out into the interstitial space via increased filtration. This overwhelms lymphatic drainage, causing edema, because the increased capillary hydrostatic pressure drives fluid out, therefore C is correct, rather than decreased interstitial pressure reducing edema.

• A patient on long-term antibiotics develops neurological symptoms including ataxia and confusion. Which mechanism explains why these symptoms arise following antibiotic use in this context?
• Why does blood pressure remain elevated after initial sympathetic nervous system activation subsides in essential hypertension?
• Why does neuronal damage in neurodegenerative diseases often spread beyond the initially affected area of the brain?
• Why does chronic cytokine exposure promote tumor growth, rather than triggering immune clearance?
• Why does pancreatic enzyme activity sharply decrease as chyme enters the jejunum in a patient with untreated celiac disease?
• A patient with a rare genetic defect lacks functional T-helper cells. Which immunological outcome is most likely, hindering antibody production against a novel viral infection?