A patient with a genetic mutation has reduced levels of functional fibrinogen. Which outcome will result from this deficiency after a blood vessel injury?

💡 Explanation

Reduced fibrinogen impairs the final stage of the coagulation cascade, preventing stable fibrin clot formation, because fibrinogen is converted to fibrin by thrombin. Therefore, impaired clot formation will result, rather than increased neutrophil chemotaxis, thromboxane A2 production, or enhanced plasminogen activation.

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