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← Human Body & HealthA patient with chronic kidney disease develops hyperkalemia. Which mechanism most directly explains why impaired renal function causes this electrolyte imbalance?
A)Increased aldosterone receptor sensitivity
B)Reduced potassium excretion in urine✓
C)Enhanced potassium reabsorption in nephron
D)Elevated distal tubule flow rate
💡 Explanation
Hyperkalemia arises in renal failure because the kidneys' ability to excrete potassium is reduced; therefore, potassium accumulates in the blood. This is due to impaired potassium secretion into the distal tubule and collecting duct, rather than increased reabsorption or altered aldosterone sensitivity.
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