A population of *Pseudomonas aeruginosa* colonizes a catheterized patient's bladder; antibiotic treatment begins. Which outcome is most likely as mutation rate rises under antibiotic selective pressure?

💡 Explanation

Efflux pump overexpression becomes more frequent because mutations conferring increased expression provide a selective advantage under antibiotic exposure; this reduces intracellular antibiotic concentration, therefore increasing survival rates, rather than biofilm reduction or motility increases which don't directly counteract the antibiotic's mechanism.

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