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Human Body & Health

An individual consuming a high-fat diet experiences persistent indigestion, despite normal gastric acid production. Why does pancreatic lipase secretion become insufficient in breaking down triglycerides?

A)Reduced enterokinase activates trypsinogen
B)CCK secretion directly inhibits lipase
C)Micelle formation decreases bile reabsorption
D)Impaired emulsification reduces lipase access

💡 Explanation

Inefficient emulsification reduces the surface area for lipase activity, hindering triglyceride breakdown, because lipase can only act at the interface between fat droplets and water. Therefore, lipase activity is limited, rather than directly inhibited by CCK or impacted by trypsinogen activation.

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