If a patient with a known bee sting allergy is stung again, which consequence follows due to histamine's effect on endothelial cells?

💡 Explanation

Systemic vasodilation and hypotension occur because histamine released during mast cell degranulation increases vascular permeability via endothelial cell contraction, therefore fluids leak from capillaries into tissues causing a drop in blood pressure, rather than localized vasoconstriction.

• Why does immunosuppression increase the risk of aplastic anemia following exposure to parvovirus B19?
• If a patient's adaptive immune system produces antibodies that bind to and block the PD-1 receptor on T-cells, which consequence follows regarding immune responses to cancer cells?
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• If a 55-year-old person with early presbyopia strains to read fine print, which consequence is most likely?
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