Why does immunosuppression increase the risk of aplastic anemia following exposure to parvovirus B19?

💡 Explanation

Immunosuppression increases the risk of aplastic anemia because it impairs the body’s ability to clear parvovirus B19, therefore increasing the duration and severity of erythroid progenitor infection. The persistent infection leads to sustained suppression of erythropoiesis, rather than a transient issue in immunocompetent individuals.

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