In children with chronic kidney disease, what explains why rickets can develop despite sufficient dietary vitamin D intake?

💡 Explanation

Rickets in children with kidney disease occurs due to impaired renal calcitriol production, because the kidneys are unable to convert vitamin D into its active form, calcitriol. Therefore, even with sufficient vitamin D intake, calcitriol deficiency leads to impaired calcium absorption and bone mineralization, rather than direct mineralization issues.

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