What causes reduced airflow when an asthmatic patient inhales allergens?

💡 Explanation

Histamine and leukotrienes are released during mast cell degranulation, triggering bronchospasm. Because airway constriction occurs, reduced airflow follows. Therefore, mast cell degranulation explains airflow reduction, rather than surfactant production, erythropoiesis, or elevated fibrinogen, which affect other systems.

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