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Human Body & Health

Which downstream consequence results after sustained cardiac muscle cell hypoxia?

A)Reduced ejection fraction efficiency
B)Increased baroreceptor firing threshold
C)Elevated circulating aldosterone production
D)Potentiated peripheral chemoreceptor activity

💡 Explanation

Reduced blood supply means less oxygen reaches muscle resulting in less powerful cardiac contraction. Less forceful output results from inhibited actin and myosin interaction (excitation-contraction coupling), and because the heart's pumping is subsequently impaired (lower ejection fraction), rather than changes to receptors/hormones.

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