Which outcome causes increased fracture risk when bone adapts to disuse?

💡 Explanation

Decreased mechanical load inhibits bone density homeostatis, therefore bone undergoes remodeling, which causes increased targeted osteoclast activity and bone resorption, making bone more porous and prone to fracture, rather than stronger formation or less differentiation.

• An elderly patient contracts influenza; high viral load overwhelms the initial interferon response. Which consequence follows regarding adaptive immunity?
• As a person ages, the lens in their eye stiffens; what causes reduced near-vision sharpness, rather than distance sharpness, due to this decreased lens curvature?
• If a patient has elevated leptin levels but still experiences overeating, which consequence follows?
• If a patient's immune system exhibits an overactive response to a minor allergen, producing excessive pro-inflammatory cytokines which overwhelm the body's natural regulatory mechanisms, which consequence follows?
• If a demyelinating disease slows action potential propagation in a motor neuron, which consequence follows for muscle contraction?
• Which endocrine imbalance causes ovarian hyperstimulation syndrome (OHSS)?