Why does enzymatic activity diminish sharply in the stomach if chyme isn't efficiently moved to the duodenum during digestion?

💡 Explanation

The enterogastric reflex inhibits gastric motility and secretion when chyme accumulates in the duodenum; because excessive activation reduces stomach emptying, leading to reduced enzymatic activity due to lack of substrate, therefore enzyme activity diminishes rather than alternative explanations involving acid or gastrin.

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