Why does resistance training in aging adults lead to muscle hypertrophy, despite decreased satellite cell activation?

💡 Explanation

Myokine secretion promotes muscle growth and systemic anabolic responses, counteracting age-related anabolic resistance, because myokines act as signaling molecules. Therefore, hypertrophy occurs despite reduced satellite cell activity, rather than through autophagy, mitochondrial changes, or reduced fibrosis alone.

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