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Human Body & Health

Why does vascular elasticity decrease in aging arteries, predisposing individuals to hypertension, even without significant atherosclerosis?

A)Increased collagen cross-linking predominates
B)Reduced smooth muscle cell proliferation occurs
C)Elevated nitric oxide synthase activity results
D)Fragmented elastin fibers accumulate over time

💡 Explanation

Fragmentation of elastin fibers occurs because elastase activity increases and elastin synthesis decreases with age, thereby reducing the arteries' capacity to recoil after expansion. This contrasts with atherosclerosis's plaque formation, and increased collagen would stiffen the arteries further, rather than causing fragmentation.

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