A researcher studying osteoarthritis wants to reduce pain and inflammation. If they successfully block phospholipase A2 activity in chondrocytes, which consequence follows regarding prostaglandin synthesis?

💡 Explanation

Blocking phospholipase A2 prevents the release of arachidonic acid from cell membrane phospholipids, because this is the initial step. Therefore, prostaglandin synthesis, which requires arachidonic acid, is inhibited, rather than being upregulated, thus reducing inflammation and pain.

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