Why does increased vascular permeability occur during anaphylaxis following exposure to an allergen such as bee venom?

💡 Explanation

During anaphylaxis, allergen exposure triggers IgE sensitization of mast cells, causing degranulation. This process releases histamine, which increases vascular permeability because it binds to endothelial receptors, leading to vasodilation and fluid leakage; therefore, option C is correct, rather than the T-cell or complement mediated options.

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