Why does prolonged occlusion of sebaceous follicles, as with a non-porous bandage, increase the risk of Cutibacterium acnes proliferation?

💡 Explanation

Occlusion of sebaceous follicles leads to sebum accumulation; because sebum is rich in triglycerides, it provides C. acnes with a readily available energy source for proliferation. Therefore, increased triglycerides promote bacterial growth, rather than inhibiting it via immune responses or limiting bacterial metabolism with decreased oxygen.

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