Why does small intestinal bacterial overgrowth (SIBO) sometimes lead to deficiencies in fat-soluble vitamins after gastric bypass surgery?

💡 Explanation

SIBO disrupts normal fat digestion because bacteria deconjugate bile acids, which impairs micelle formation, a critical step for fat-soluble vitamin absorption. Therefore, vitamin deficiencies occur, rather than increased enzyme activity or efficient bile recirculation, as the digestive processes are negatively affected.

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