Why does the luteal phase sometimes appear shortened in women undergoing fertility treatments with exogenous FSH?

💡 Explanation

Elevated FSH levels during fertility treatments can cause multiple follicles to mature simultaneously, leading to supraphysiological estrogen levels. This excess estrogen can trigger premature luteolysis because it interferes with the normal corpus luteum function, therefore shortening the luteal phase, rather than direct FSH inhibition of progesterone or effects on LH receptors.

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