An obese patient undergoes gastric bypass surgery; which outcome involving gut hormones is most likely in the long term?

💡 Explanation

Gastric bypass alters gut anatomy, increasing the delivery of nutrients to the distal small intestine, because this stimulates increased secretion of GLP-1. Therefore, enhanced GLP-1 secretion and action improves glucose homeostasis and satiety, rather than reducing leptin sensitivity or acutely increasing ghrelin.

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