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Human Body & Health

Why does molecular mimicry sometimes trigger autoimmune responses, leading to self-tissue damage?

A)Increased antibody production by B-cells
B)Enhanced antigen presentation by dendritic cells
C)Regulatory T cell tolerance breakdown occurs
D)Heightened cytokine storm from macrophages

💡 Explanation

Autoimmune responses arise from molecular mimicry when regulatory T cell function fails; because these cells normally suppress autoreactive lymphocytes, a breakdown in their tolerance mechanisms allows self-reactive T cells to attack tissues. Therefore, self-tissue damage occurs, rather than a normal immune response.

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